ACCEPT:

• Unless the donor has had a thrombotic episode

PERMANENTLY EXCLUDE: 

• If the donor has had a thrombosis

ADDITIONAL INFORMATION

Factor V Leiden is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an increase in blood clotting (hypercoagulability). Due to this mutation, protein C, an anticoagulant protein that normally inhibits the pro-clotting activity of factor V, is not able to bind normally to factor V, leading to a hypercoagulable state, i.e., an increased tendency for the patient to form abnormal and potentially harmful blood clots

SEE IF RELEVANT

• THROMBOPHILIA
• THROMBOSIS