ACCEPT:
- Unless the donor has had a thrombotic episode
PERMANENTLY EXCLUDE:
- If the donor has had a thrombosis
ADDITIONAL INFORMATION
Factor V Leiden is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an increase in blood clotting (hypercoagulability). Due to this mutation, protein C, an anticoagulant protein that normally inhibits the pro-clotting activity of factor V, is not able to bind normally to factor V, leading to a hypercoagulable state, i.e., an increased tendency for the patient to form abnormal and potentially harmful blood clots
SEE IF RELEVANT
| IBTS/MEDD/DSGDE/0001 | Attachment 4.162 | Ver 1.1 |