PERMANENTLY EXCLUDE:

• If donor has G-6-P-D deficiency

ADDITIONAL INFORMATION

Glucose-6-phosphate dehydrogenase deficiency is a genetic disorder that occurs almost exclusively in males. It mainly affects red blood cells and in affected individuals, a defect in an enzyme called glucose-6-phosphate dehydrogenase causes red blood cells to break down prematurely (haemolysis). The most common medical problem associated with glucose-6-phosphate dehydrogenase deficiency is hemolytic anemia, which occurs when red blood cells are destroyed faster than the body can replace them. This type of anaemia leads to paleness, yellowing of the skin and whites of the eyes (jaundice), dark urine, fatigue, shortness of breath, and a rapid heart rate. These symptoms may compromise the safety of the donor and recipient and therefore donors with G-6-P-D are permanently excluded