Ambition
Pilot innovative research and developmental initiatives that inform the future organisational strategic direction
Objectives
- Determine the future role of IBTS in the provision of advanced cellular therapies
- Provide the resources for high-impact medical & scientific research
- Support the implementation of new state-of-the-art laboratory methodologies
- Develop a framework to pilot innovation initiatives
Action plan
- Virus-Specific Cytotoxic T Cells production: Re-purpose cells collected in apheresis cones to produce Cytomegalovirus and Epstein-Barr virus specific cytotoxic T lymphocytes as a cellular therapy for immunocompromised patients
- ATMP Regulatory and manufacturing pathway: Collaborate on developing donor, regulatory and manufacturing frameworks, that include the blood services, for the provision of ATMPS.
- Allogeneic Donor Qualification: Establish standard criteria for qualifying donors for allogeneic cell donation.
- Irish ABO & Coagulation Strategic Partnership (iABC): Understand the impact of ABO on donors with heavy menstrual bleeding and contribute the shared understanding of the underlying biochemical mechanisms by which ABO impacts bleeding and haemostasis.
- Publish laboratory developments: Support the publication of newly implemented testing and production methodologies
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Staff led small-scale innovation: Create a framework for supporting and cataloguing staff-led innovative initiatives