HLA Variation and Disease

Human Leukocyte Antigen (HLA) Variation and Disease

Aims

  • To determine the distribution of Human Leukocyte Antigen (HLA) genotypes in Irish Donors
  • To compare donor HLA profiles with those required by transplant recipients
  • To investigate the associations between HLA types and disease presentation and progression

Key findings 

    On-going Research

    • Association of HLA with progression of paediatric type 1 diabetes
    • Link between paediatric hepatitis of unknown origin and HLA.
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