Characterisation of Platelet-Derived Extracellular Vesicles

Characterisation of Platelet Derived Extracellular Vesicles


The factors that influence the quality of blood components are incompletely understood, leading to waste and sub-optimal clinical outcomes. This project aims to answer the following research question:

"What are the molecular changes that occur in platelet-pack associated extracellular vesicles, and how can these be exploited to improve platelet quality and reduce waste?"


  • Define the physical, biochemical and functional changes that occur to platelet-derived extracellular vesicles (PEV) during the preparation, processing and storage of donated blood.
  • Develop models to more accurately predict a donor-associated lifespan of blood products supporting platelet component preservation.

Principal Investigators

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