Health Research Projects that use Donated Material

Institution

Principal Investigator

Health Research Aim

Research Ethics Reference Number

Donated Material

Donor Data Shared with Health Researcher

Health Research Focus

Donation ID

Date of Donation

Blood Group

Donor Age

Donor Gender

Dublin City University

Michael Freeley

Biotherapeutics for Inflammatory Skin Diseases

DCUREC2025/208; DCUREC2025/209; DCUREC2025/210

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Karen English

Investigating immune system activation in human immune cells

BSRESC-2024-38848

Buffy Coat, Apheresis Cones

X

X

X

X

X

Cell Function & Biochemistry; Immune System

Marion Butler

Age and Sex Differences in Immune Signalling Pathways.

BSRESC-2021-2452643

Buffy Coat, Plasma

X

X

X

Immune System

Mark Robinson

Analysis of the glycome of immune cells and immune molecules in relation to the impact on inflammation and anti-tumour immunity.

BSRESC-2024-37562

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

National Institute for Bioprocessing Research and Training

Clair Gallagher

Biotherapy research and development.

LS-LRB-25-046-Bones

Buffy Coat

X

X

X

X

X

Cell Function & Biochemistry; Immune System; Bioengineering Systems & Tools

Michelle de Oliveira Chain

Increase the efficiency, purity, and viability in the isolation protocols for T cells, Natural Killer cells, Monocytes, and CD34⁺ cells.

TCD ID: 260208

Buffy Coat, Apheresis Cones

X

X

X

Cell Function & Biochemistry; Immune System; Bioengineering Systems & Tools

Royal College of Surgeons of Ireland

Aamena Mejevdiwala

solation of Peripheral T-Lymphocytes, Peripheral Blood Mononuclear Cells (PBMCs), Macrophages and Platelets from Buffy Coat Samples for In-Vitro Characterization of Biomaterials

202511016

Buffy Coat

X

X

X

Immune System

Gemma Leon

Exploiting APC signalling to mitigate colitogenic CD4+ T-cell thromboinflammatory activity

GEN/193/11

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Ingmar Schoen

Understanding Cold-Stored Platelets

REC202301015; RCSI-REC-1504

Platelets

X

X

X

Cell Function & Biochemistry; Transfusion Medicine

Patricia Lopes

von Willebrand factor glycosylation and biological functions

AE19127/P081

Buffy Coat, Platelets, Plasma

X

X

X

Cell Function & Biochemistry;

Trinity College Dublin

Aideen Long

tHe pErsonalised Active ceLl thErapy paraDigm (HEALED)

Project ID 0369

Buffy Coat

X

X

X

X

X

Cell Function & Biochemistry; Immune System

Aisling Dunne

Evaluation of Novel Modulators of Oxidative Stress as add-on Pharmacotherapies for Inflammatory Disease Ethics

B1-LS-010923

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Andreea Petrasca

Characterising immune and metabolic pathways in inflammatory skin disease

STEM REC is 4333

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Anne McGettrick

Role of immunometabolites in the immune response

3135_FSTEMREC_AM_SEPT2024.

Buffy Coat

X

X

X

X

X

Immune System

Aoife McLoughlin

Understanding macrophage responses to biomaterial applications

1103_2024

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System; Bioengineering Systems & Tools

Chloe Mullen

Isolation of human immune cell subsets for in-vitro analysis of activation responses

251109

Whole Blood

X

X

X

Cell Function & Biochemistry; Immune System

Eric Downer

Devekopment of inflammatory assays in immune cells to assess novel therapeutics.

REC reference: 16/47

Buffy Coat

X

X

X

X

X

Cell Function & Biochemistry; Immune System

Frederick Sheedy

Assessing the Impact of Innate Immune Training on Immune Function(s)

TCD - Faulty STEM 12th August 2022

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Joyce Barry

Investigating the applicability of cytokine-induced memory-like NK cell therapy for oesophageal adenocarcinoma

2023-Mar-26532653 (Project ID is 215)

Buffy Coat

X

X

X

X

X

Immune System

Kiva Brennan

Developmental changes in PRR activity of the Innate Immune System in children (PARIS-study)n

250503

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Lorraine Smith

Investigating the effect of electroporation on the Barrett's Oesophagus microenvironment

277

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Mary O'Sullivan

HUMAN IMMUNE CELL RESPONSE TO MYCOBACTERIA AND VIRUSES

20230102

Buffy Coat, Whole Blood, Apheresis Cones

X

X

X

Cell Function & Biochemistry; Immune System

Michael Carty

Harnessing innate immunity to treat invasive fungal infections

241111

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System; Artificial Intelligence and/or Machine-Learning

Patrick Walsh

Isolation of human T cell subsets and in vitro analysis of activation responses.

REF251009

Buffy Coat

X

X

X

X

X

Immune System

Rachel McLoughlin

Profiling Immune Signatures Predictive of Infection Outcomes in Staphylococcus aureus Infection

2486_FSTEMREC_BM_JULY2024

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Sharee Basdeo

Defining human innate and adaptive immune function to infectious diseases

2238

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Tracey Claxton

Investigation of Molecular and Genetic Contribuotrs to Arthritic Disease

Project ID42

Buffy Coat

X

X

X

X

X

Immune System

Viviana Marzaioli

Investigating phagocytes activation in autoimmune rheumatic diseases

SVUH REC approval granted

Buffy Coat, Whole Blood

X

X

X

Cell Function & Biochemistry; Immune System

University College Cork

Asma Amamou

AUGMENT Project - Understand the contribution of Ikaros transcription factors in myeloid population

2303

Buffy Coat

X

X

X

X

X

Cell Function & Biochemistry; Immune System

Cathriona Foley

Molecular and Cellular Characterization of Blood from Healthy Donors and Exploration of Surgical Adjuvants Harnessing the Postoperative Immune Response

ECM 4 (f) 28/03/2023 & ECM 3 (e) 15/05/2025

Buffy Coat, Whole Blood

X

X

X

Cell Function & Biochemistry; Immune SystemLaboratory Test Development

David Zelaya

Access to donated biological material will allow us to validate and standardize our assays under conditions that accurately reflect real human samples. This will ensure our methods are robust and reliable before applying them to studies on the immunological effects of bacterial species.

2601

Buffy Coat, Platelets, Whole Blood, Plasma

X

X

X

Immune System

Liam O'Mahony

Investigation of how gut microbes and microbe-derived metabolites Influence human immune responses

2301

Buffy Coat, Apheresis Cones

X

X

X

X

X

Immune System

Rekha Gautam

Spectroscopic Non-invasive Assessment of Stored Blood Quality – SAFE BLOOD.

ECM 4 (s) 05/04/2022; ECM 5 (10) 05/04/2022

Plasma, Red Cell Concentrate

X

X

X

Bioengineering Systems & Tools; ; Transfusion Medicine

University College Dublin

Adam Byrne

Defining the role of immune cells in chronic lung disease

SVUH REC 05/03/2025

Buffy Coat

X

X

X

Cell Function & Biochemistry; Immune System

Eoin Cummins

Gene expression analysis of human airway-associated cells following clinically indicated bronchoscopy

RS19-079

Buffy Coat, Platelets, Plasma

X

X

X

Cell Function & Biochemistry; Immune SystemLaboratory Test Development

Fiona Freeman

New Therapeutic Strategies for Pediatric Osteosarcoma

LS-LR-24-199

Buffy Coat

X

X

X

Immune System; ; Bioengineering Systems & Tools

Luke Conroy

Blood Sampling for Research on Resolution of Inflammation

LS-23-17-deGaetano

Buffy Coat, Whole Blood

X

X

X

Cell Function & Biochemistry; Immune System

Sarah Robertson

A systems biology network-based approach for personalized immunotherapy in melanoma, lung cancer, and bladder cancer

264-LS-SD-25-Robertson-Kholodenko

Buffy Coat

X

X

X

X

X

Cell Function & Biochemistry; Immune System; Artificial Intelligence and/or Machine-Learning

University of Galway

Karen Doyle

Studying the blood clots that cause strokes

2017.03.006

Buffy Coat, Platelets, Whole Blood, Plasma

X

X

X

Cell Function & Biochemistry; Artificial Intelligence and/or Machine-Learning; Laboratory Test Development

Mihai Lomora

Research on stem cells, mini brains, and human blood (part of a wider MSCA DN project: Tiny Machines Working to Elucidate Mechanisms of Cerebrovascular Pathologies)

2025.05.009

Whole Blood

X

X

X

X

X

Bioengineering Systems & Tools