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Donor Data controller: Irish Blood Transfusion Service
Research Data controller: Research Organisation
Health Research Projects approved to use Donated Material
Institution |
Principal Investigator |
Health Research Aim |
Research Ethics Reference Number |
Donated Material |
Donor Data Shared with Health Researcher |
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Donation ID |
Date of Donation |
Blood Group |
Donor Age |
Donor Gender |
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Dublin City University |
Achilleas Floudas |
Examine the role of the immune system and metabolism at the inflamed joint in order to identify novel opportunities for targeted therapeutic intervention for arthiritis |
230523BSC - DCU |
Buffy Coats, Whole Blood |
x |
x |
X |
||
Denis Collins |
Examine the impact of intratumoural bacteria on the efficacy of targeted therapy using gastrointestinal cancer models and techniques. |
DCUREC/2017/116 |
Buffy Coats |
x |
x |
x |
|||
Karen English |
Investigate the capacity for human mesenchymal stromal cells (MSCs) to suppress immune cell function. |
BSRESC-2022-2482563 |
Buffy Coats |
x |
x |
x |
|||
Maynooth University |
Marion Butler |
Age and Sex Differences in Immune Signalling Pathways |
BSRESC-2021-2452643 |
Buffy Coats |
x |
x |
x |
x |
x |
Mark Robinson |
Identify the glycans on immune molecules and determin their ability to interact with tumour cells. |
REC 37562 |
Buffy Coats |
x |
x |
x |
|||
Royal College of Surgeons of Ireland |
Annie Curtis |
Harness extracellular vesicles, derived from metabolically modulated macrophages, to promote the regenerative bone healing. |
REC202303001 |
Buffy Coats |
x |
x |
x |
x |
x |
Gerard Curley |
Develop a laboratory model for Acute Respiratory Distress Syndromw and examine the impact of novel therapeutics on injury |
REC202405016 |
Whole Blood |
x |
x |
x |
|||
Ingmar Schoen |
Assess the impact of storage conditions on platelet function and clearance |
RCSI REC202301015 |
Platelets |
x |
x |
x |
|||
James O’Donnell |
Investigate how ABO sugar antigens on Von Wilebrand Factor (VWF) influence its biological function and clearance. |
REC1315 and AE19136/P040 |
Buffy Coats, Plasma |
x |
x |
x |
|||
Marco Monopoli |
Expose nano partices to donated plasma and understand how their behaviour changes. |
REC 1246b |
Plasma |
x |
x |
x |
|||
Roger Preston |
Examine the hyper coagulable and immunothrombotic state evident in Myeloproliferative Neoplasms Patients |
SJH/TUH/JREC/2315 |
Buffy Coats |
x |
x |
x |
|||
Technological University of Dublin |
Claire Wynne |
Role of Platelet-Derived Extracellular vesicles in tranfusion |
LEWS-024-225 |
Platelets |
x |
x |
x |
x |
x |
Trinity College Dublin |
Aideen Long |
CharacteriseT cell responses to viral peptides in patients with Long COVID |
REC 20-012-AF1/COV |
Buffy Coats |
x |
x |
x |
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David Hoey |
Investigate the contribution of dynamic biophysical cues, predicted to occur during the early phase of bone repair, on human blood-derived macrophage. |
2306_FSTEMREC_SPDH_2022 |
Buffy Coats |
x |
x |
x |
|||
Fred Sheedy |
To investigate how activation and training of monocytes and other innate immune cells to better respond to infection is affected by metabolic changes |
TCDFSTEMREC_12082022_ML |
Buffy Coats |
x |
x |
x |
|||
Jacintha O'Sullivan |
Investigate the new therapy of calcium electroporation in Barrett's Oesophagus |
REC 0277 |
Buffy Coats |
x |
x |
x |
|||
Jacintha O'Sullivan |
The effects of electroporation on the secretome of explant models of gastrointenstinal cancers |
2023-Apr-27372737 Upper GI , 2023-Mar-26532653 Lower GI |
Buffy Coats |
x |
x |
x |
|||
Jean Fletcher |
Characterising immune and metabolic pathways in inflammatory skin disease |
BI-AP-300924a |
Buffy Coats |
x |
x |
x |
|||
Joanne Lysaght |
Profile the immune component of pre-malignant pancreatic cysts for earlier detection and diagnosis of pancreatic cancer |
2023-Mar-26532653 |
Buffy Coats |
x |
x |
x |
|||
Joseph Keane |
Study the immune cell responses to infection with mycobacteria, SARS CoV-2 and other pathogens. |
REC 20230102 |
Buffy Coats, Whole Blood |
x |
x |
x |
|||
Luke O'Neill |
Examine the effect of metabolism within the cells on the innate immune response. |
BI-AMG-300924 |
Buffy Coats |
x |
x |
x |
|||
Mary Canavan |
Understand the metabolic pathways that are involved in immune cell activation, differentiation and proliferation. |
REC 2951 |
Buffy Coats |
x |
x |
x |
|||
Michael Monaghan |
Develop an in vitro drug screening platform for Mycardial Infarction. |
Faculty of STEM- TCD 2022-06-07 |
Buffy Coats |
x |
x |
x |
|||
Nicola Gardiner |
Monitor the patients' immune function following cellular therapy (CAR-T) |
REC 0535 |
Buffy Coats |
x |
x |
x |
x |
x |
|
Padraic Fallon |
The blood will be used as healthy controls in research project on Haemophilia |
REC 20180403 |
Whole Blood |
x |
x |
x |
|||
Rachel McLoughlin |
Understand the host immune reponse to and immunomodulatory capacity of Staphlococcus aureus infection. |
REC 140622 |
Buffy Coats |
x |
x |
x |
|||
Aisling Dunne |
Investigate the immune response to inflammatory stimuli, relevant to various inflammatory diseases |
B1-LS-010923 |
Buffy Coats |
x |
x |
x |
|||
Clair Gardiner |
Understand how Natural Killer (NK) cells work and are how they regulated in healthy normal individuals |
TCDFEMSREC_ 02032020_Gard_Slat |
Buffy Coats, Whole Blood |
x |
x |
x |
|||
Eric Downer |
Assess innate immune signature in immune cells from control cases, and individuals with disease. |
REC REF: 16/47 / 3503 |
Buffy Coats, Whole Blood |
x |
x |
x |
|||
Kathy Gately |
Characterise liquid biopsy in patients with lung cancer and healthy individuals |
REC 041018/8804 |
Buffy Coats, Plasma, Whole Blood |
x |
x |
x |
|||
Lorraine O'Driscoll |
Investigate the effect of gastric cancer patient plasma derived extracellular vesicles (EVs) on T-cells |
2023-Mar-26532653 (Project ID if needed is 215) |
Buffy Coats |
x |
x |
x |
|||
Melissa Conroy |
Investigate the effect of in vitro cytokine treatment on healthy donor naturl killer cells |
2023-Mar-26532653 (Project ID 215) |
Buffy Coats |
x |
x |
x |
|||
Sarah Doyle |
Characterise the role of the immune system in Age-related Macular Degeneration |
REC 210308 |
Buffy Coats |
x |
x |
x |
|||
Sharee Basdeo |
Characterise the interplay between myeloid and lymphoid cells in healthy people and those during and post disease. |
REC 20200802 |
Buffy Coats |
x |
x |
x |
|||
Viviana Marzaioli |
Characterise the functionality of Rheumatoid Arthritis and Psoriatic Arthritis derived monocytes |
SVUH REC approval granted, |
Buffy Coats |
x |
x |
x |
|||
University College Cork |
Cathriona Foley |
Characterse postoperative inflammation and wound healing. |
ECM 4 (f) 28/03/2023 |
Red Cell Concentrate, Buffy Coats, Platelets, Plasma, Whole Blood |
x |
x |
x |
||
Fergus McCarthy |
Non-invasive detection of lactate using bio-photonics in whole-blood |
ECM 4 (r) 06/02/20 |
Red Cell Concentrate, Buffy Coats, Platelets, Plasma, Whole Blood |
x |
x |
x |
|||
Jens Walter |
We are studying how bacteria and their metabolites influence the immune system. |
REC 2302 |
Buffy Coats, Whole Blood |
x |
x |
x |
|||
Liam O'Mahony |
Investigate how bacterial components and metabolites influence innate and adaptive immune responses. |
REC 2301 |
Buffy Coats |
x |
x |
x |
|||
Subrata Ghosh |
Understand how the gut microbiome regulates inflammatory bowel disease |
REC 2303 |
Buffy Coats |
x |
x |
x |
|||
Vitaliy Mykytiv |
Role of Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in coagulation and haemostasis. |
ECM 4 (a) 01/08/2023 |
Buffy Coats |
x |
x |
x |
|||
John Higgins |
Quantify blood loss during obstetric complications. |
ECM 4 (q) 12/09//2023 & ECM 3 (r) 24/10/2023 |
Whole Blood |
x |
x |
x |
|||
University College Dublin |
Adam Byrne |
Monocyte and Macrophage Metabolism in Lungs. |
SVUH REC 05/03/2025 |
Buffy Coats, Whole Blood |
x |
x |
x |
||
Eoin Cummins |
Investigation of the effect of hypoxia and hypercapnia on human immune cells |
RS19-079 |
Buffy Coats, Whole Blood |
x |
x |
x |
|||
Fiona Freeman |
Develop novel therapeutics for pediatric bone cancer, osteosarcoma |
LS-LR-24-199-Odonoghue-Freeman |
Buffy Coats |
x |
x |
x |
|||
Guenther Eissner |
Investigate the COVID-19 effect on lung endothelial cells |
RES 528 |
Buffy Coats |
x |
x |
x |
|||
Margaret Mc Gee |
Investigate the role of extracellular vesiciles in B cell malignancies |
LS-E-21-115-Sheridan-McGee |
Buffy Coats, Whole Blood |
x |
x |
x |
|||
Michael keane |
PBMC isolation from buffy coat to then isolate fibrocytes for primary cell cultire |
RES 528 |
Buffy Coats |
x |
x |
x |
|||
Virginie Gautier |
Develop novel HIV Cure strategies that target and reduce the size of the HIV reservoirs |
LS-LR-22-246-dAutume-Gautier |
Buffy Coats |
x |
x |
x |
|||
University of Galway |
Daniel O'Toole |
Characterise the immunomodulatory properties of different cell types |
C.A. 3199 |
Buffy Coats |
x |
x |
x |
||
John P. Dalton |
Investigate the therapeutic potential of helminth-derived immunomodulatory properties in the treatment of inflammatory diseases. |
REC 2022.10.018 |
Buffy Coats |
x |
x |
x |
|||
Karen Doyle |
Characteriste stroke clots to better leading to new and improved stroke treatments. |
REC 17-MAR-06 |
Buffy Coats, Platelets, Whole Blood |
x |
x |
x |
|||
Radka Fahey (Saldova) |
Investigate the role of glycosylation on T-cells function |
277-LS-SD-25-Fahey |
Buffy Coats |
x |
x |
x |